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We extracted data as test positive or test negative results for Down’s and non Down’s pregnancies allowing estimation of detection rates (sensitivity) and false positive rates (1 specificity). We performed quality assessment according to QUADAS (Quality Assessment of Diagnostic Accuracy Studies) criteria. We used hierarchical summary ROC (receiver operating characteristic) meta analytical methods to analyse test performance and compare test accuracy.

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Philosopher, polymath, educator, synthesist, founder. These are just some of the words used to describe Aristotle, the 4th century BCE Greek luminary who (along with Plato) is known as the of Western philosophy. With subjects ranging from physics steroids, biology, and astronomy to logic steroids, ethics, politics, and metaphysics, there is scarcely any field of study or subject that he did not have a significant and lasting impact on..

steroid side effects AbstractMeasuring the accuracy of diagnostic tests is crucial in many application areas including medicine, machine learning and credit scoring. The receiver operating characteristic (ROC) surface is a useful tool to assess the ability of a diagnostic test to discriminate among three ordered classes or groups. In this paper, nonparametric predictive inference (NPI) for three group ROC analysis for ordinal outcomes is presented. steroid side effects

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